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http://www.val202.si...etna-direktiva/

 

Kmalu bodo zelo verjetno tudi pri nas na škatlicah cigaret nazorno prikazane škodljive posledice kajenja, slikovno in besedilno zdravstveno opozorilo bo moralo pokrivati tri četrtine embalaže. Države se bodo lahko odločile za enotno embalažo cigaret.

Evropska komisija namreč pripravlja spremembo direktive o tobačnih izdelkih, ki bo precej strožja do izdelave, predstavitve in prodaje.

Edited by Kotalko
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http://www.drogart.o...n-presnova-alko

Vabljeni na predavanje o nevrotoksičnosti alkohola v sredo, 23.1.2013 ob 18.00 v klubu Tiffany (AKC Metelkova mesto, )

Na predavanju bomo razložili, kako deluje alkohol na nivoju nevrotransmiterjev oziroma živčnih prenašalcev. To je dobro vedeti zato, da potem lažje razumemo, zakaj pride do odvisnosti od alkohola, mačka, povišane tolerance in ostalih nevšečnosti, ki spremljajo uporabo alkohola.

 

Obljubim, da bo zanimivo;)

 

Zaradi lažje organizacije so obvezne predhodne prijave na simona@drogart.org, preko telefona na 01 439 72 70 ali osebno v DrogArt info točki (Prečna ulica 6, Ljubljana).

Edited by Kotalko
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Ne da se mi prevajat, če bo koga zanimal si bo že prebral pa vprašal, če mu ne bo kaj jasno.

V grobem se gre za to, da se špekulira, da bi lahko uporaba marihuane bila eden izmed dejavnikov tveganja za možgansko kap. Prihajalo naj bi do zožanja žil, ki se popravi po prenehanju uporabe. Kako? Pojma nimajo, zadeva je še čisto v povojih. Zato je tudi ne vzeti za definitvno.

 

Consider Cannabis as Cause of Stroke in Younger Patients

Sue Hughes; Jan 22, 2013

 

Cannabis-related stroke is not a myth, and cannabis use should be considered a risk factor for ischemic stroke, a new review of the literature concludes.

The review, published in the February issue of Stroke, was conducted by a team led by Valérie Wolff, MD, from the University Hospital of Strasbourg, France.

Dr. Wolff commented to Medscape Medical News that because most cannabis smokers are young, patients under 45 years of age presenting with symptoms of stroke should be asked about cannabis use and have their urine tested for cannabinoids.

"It is important to establish if cannabis has been the cause as they can reduce their risk of a subsequent stroke if they stop using the drug," she said.

 

The Tip of the Iceberg

The authors note that 59 case reports of cannabis-related stroke (mean age, 33 years) have been described. Most cases were in men, with a male-to-female ratio of 4.9:1. Of the 59 cases, 49 were classed as ischemic strokes, 5 were transient ischemic attacks, and 1 was a hemorrhagic stroke; in 4 patients, a diagnosis of stroke was suspected but not confirmed because no neuroimaging was done.

They add that in many cases the strokes appeared to have occurred while the drug was actually being smoked, or within half an hour of smoking, which is in accordance with another study showing that cannabis increases myocardial infarction 4.8-fold during the hour after its intake.

Dr. Wolff told Medscape Medical News that although only these few cases of stroke associated with cannabis use have been documented, this is probably just the tip of the iceberg. "Nobody is looking for it, and if you don't look you won't find it. Neurologists are not thinking about cannabis as a possible cause of stroke so they don't ask patients about it."

The authors caution that the reality of the relationship between cannabis and stroke is, however, complex because other confounding factors have to be considered. These include potential triggering factors of sexual activity or concomitant alcohol consumption. There may also be genetic predisposition to susceptibility to stroke from cannabis use, but this requires more study.

Dr. Wolff estimates that less than 10% of strokes occur in patients under 45 years of age. These strokes are generally caused by cardioembolism or cervical arterial dissection. Around 30% to 60% of strokes in this age group are considered cryptogenic, with no established cause. But in many of these cases, the best diagnostic procedures may not have been performed, she says.

In a previous study, Wolff and colleagues examined the vessels in the brain very closely and found that just 12% of strokes could be classed as cryptogenic. Of these, about 30% may have been caused by cannabis use. "So it is not an insignificant number," Dr. Wolff noted.

 

Mechanism: Multifocal Intracerebral Stenosis

In terms of mechanism, Dr. Wolff says cannabis appears to be associated with multifocal intracerebral stenosis, which can cause a stroke. "We have seen these stenoses in people who are regular cannabis smokers and when they stop smoking the stenoses disappear. How cannabis causes the stenosis, we do not know. This needs to be studied," she said.

"The stenoses are caused by shrinkage of the blood vessels and can occur in several different areas of the brain. It appears that cannabis may cause the arteries to constrict. These stenoses can be difficult to see. They can be detected with magnetic resonance angiography, but careful scrutiny of the vessels is required. Many are missed," Dr. Wolff added.

"In light of this review, cannabis has to be considered as harmful and the cerebrovascular risk when cannabis is consumed is probably underestimated," the authors conclude.

To confirm the link, they call for an epidemiologic study to determine the incidence of multifocal intracerebral stenosis, complicated or not by stroke, in the general population and in cannabis users.

To confirm the diagnosis, it is necessary to perform magnetic resonance angiography in the acute stage of stroke to search for intracranial stenosis, the authors say. Thereafter, control vascular imaging is important to evaluate the reversibility of vascular abnormalities. However, when there is a doubt between stenosis and arterial artifacts, conventional angiography with 3-dimensional reconstructed images is needed to confirm diagnosis of stenosis, they add.

 

The authors have disclosed no relevant financial relationships.

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V Avstraliji zasegli rekordno količino amfetaminov

 

Ulična vrednost mamila okoli 340 milijonov evrov

28. februar 2013 ob 12:41

Sydney - MMC RTV SLO

Avstralske oblasti zasegle doslej največjo količino metamfetaminov. Več kot pol tone mamil je bilo skritih v pošiljki iz južne Kitajske.

 

http://www.rtvslo.si...etaminov/303389

Edited by Kotalko
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Kiwis on drugs: a blueprint for the future?

 

http://www.bbc.co.uk/news/uk-21615971

 

Unlike Britain, they have concluded that a "long-term and more effective solution" is to license the importation, manufacture and sale of all new psychoactive products.

In the same way as pharmaceutical companies must apply for a licence to sell a drug after extensive testing, so suppliers of legal highs will be able to market products in New Zealand if they can demonstrate they present a low risk of harm.

Rather than trying to ban every new drug that turns up, the legislation shifts responsibility to the manufacturer and the retailer.

Just as a bottle of aspirin can only be sold in certain outlets with all the warnings of the risks on the label, so recreational drugs will be available over the counter in New Zealand later this year.

 

:ourajt: KONČNO se je začel!

Edited by drogfart
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Kiwis on drugs: a blueprint for the future?

 

http://www.bbc.co.uk/news/uk-21615971

 

 

 

Just as a bottle of aspirin can only be sold in certain outlets with all the warnings of the risks on the label, so recreational drugs will be available over the counter in New Zealand later this year.

 

:ourajt: KONČNO se je začel!

 

Da posvetim še jaz.

 

Sem posredoval članek dobremu znancu iz nove zelandije ki trenutno pomaga opremljati legalen laboratorij za tesitranje in razvijanje novih RC-jov

Sam zakon ni toliko da bi bili ti produkti legalizirani, temveč da bi bili prepovedani za prodajo dokler se jih ne ustrezno testira ter da državni organ poda zeleno luč.

Torej naloga tega organa bi bila da pregleda rezultate ekstenzivnih testov ( extra expensive ) in nato potrdi da je sam izdelek varen za človeško uporabo. Na srečo živi na NZ ekstremno pobožen multi milijonar katerega sveta naloga je da bi naredil droge varne za človeka in njegovo podjetje je pripravljeno investirati miljone v testiranja. Trenutno se testira metilon.

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7-letna deklica je padla na testu za droge, pozitivna je bila na metadon, PCP in marihuano.

 

 

FORT WAYNE, Ind. (AP) — Authorities in Indiana say a 7-year-old girl tested positive for PCP and other drugs after she was taken to a hospital emergency room in Fort Wayne.

 

Department of Child Services spokeswoman Stephanie McFarland said Friday that the agency has had “prior contact” with the child’s family but she couldn’t comment further.

 

The Journal Gazette says no criminal charges have been filed. A police report says officers and a DCS official went to Parkview Hospital Randallia on Wednesday after the child tested positive for methadone, marijuana and Phencyclidine, a narcotic commonly known as PCP.

 

The police report says the child’s mother refused to talk to officers, but officials were investigating whether another caretaker may have been involved and the DCS intended to interview the other children in the girl’s home.

 

http://www.indystar.com/viewart/20130302/NEWS02/303020042/Report-7-year-old-girl-tests-positive-drugs

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Celjski kriminalisti so zaradi gojenja konoplje ovadili 36-letnega moškega, doma z območja Dravograda. Po neuradnih, a zanesljivih informacijah je dejanja osumljen nekdanji policist, celo pripadnik posebne enote policije Gregor Kac, ki je obenem vidni član stranke SDS in družinski prijatelj nekdanje poslanke Alenke Koren Gomboc.

http://www.dnevnik.si/slovenija/v-ospredju/vidni-clan-sds-gojil-konopljo

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Novartis loses landmark India patent case on Glivec, govt hails 'historic' SC verdict

http://timesofindia.indiatimes.com/business/india-business/Novartis-loses-landmark-India-patent-case-on-Glivec-govt-hails-historic-SC-verdict/articleshow/19324487.cms

India has refused protection for Glivec on the grounds that it is not a new medicine, but an amended version of a known compound. By contrast, the newer form of Glivec has been patented in nearly 40 countries including the United States, Russia and China.

 

 

Reckitt loses U.S. bid to block generic heroin addict drug

http://www.reuters.com/article/2013/02/25/us-reckittbenckiser-idUSBRE91O0AW20130225

Edited by Kotalko
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Serotonin receptors offer clues to new antidepressants

 

http://www.nature.co...essants-1.12659

 

“This is huge,” says Bryan Roth, a neuropharmacologist at the University of North Carolina Chapel Hill Medical School, and a co-author of the two studies published in Sciencetoday1, 2. “Before this there was no crystal structure for any serotonin receptor. A lot of what was theoretical is now known with a great degree of certainty,” he says.

 

 

proti koncu novice je omenjen LSD...

Edited by Kotalko
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